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Perampanel, a first-in-class substance (a non-competitive AMPA receptor antagonist), is used to treat patients with epilepsy aged 12 and older. Specifically, it is used as adjunctive therapy for partial onset seizures (with or without secondarily generalized seizures) and primary generalized tonic-clonic (PGTC) seizures.
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The information detailed herein, including that with regard to active pharmaceutical ingredients , their use in treatments and possible mechanism(s) of action, was all obtained from public sources.
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