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Osimertinib mesylate

CAS 1421373-66-1
Osimertinib mesylate

General Information

Osimertinib mesylate is a methanesulfonate (mesylate) salt prepared from equimolar amounts of osimertinib and methanesulfonic acid. Osimertinib is indicated as a first line treatment of metastatic non-small-cell lung cancer with specific mutations. It demonstrated impressive results in phase IV clinical studies. Here at Teva api, the way we produce the osimertinib API is entirely green, as our ecofriendly and efficient process involves minimal isolation of intermediates. Another huge plus is that we have good control of impurities, especially genotoxic ones.


About the API

Technology Synthetic
Therapeutic category Oncology
Systematic Name N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide
Available formulations Oral Solid
Regulations
  • Japan DMF
  • Korea DMF
  • US DMF

The information detailed herein, including that with regard to active pharmaceutical ingredients , their use in treatments and possible mechanism(s) of action, was all obtained from public sources.

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